Tyck till om SwePub Sök här!
WFRF:(Skeie G)
Search: WFRF:(Skeie G) > Barricarte A > Biomarkers of folat...
- 8 of 21
- Previous record
- Next record
- To hitlist
Biomarkers of folate and vitamin B12 and breast cancer risk : report from the EPIC cohort
- Matejcic, M. (author)
- de Batlle, J. (author)
- Ricci, C. (author)
- show more...
- Biessy, C. (author)
- Perrier, F. (author)
- Huybrechts, I. (author)
- Boutron-Ruault, M. C. (author)
- Cadeau, C. (author)
- His, M. (author)
- Cox, D. G. (author)
- Boeing, H. (author)
- Fortner, R. T. (author)
- Kaaks, R. (author)
- Lagiou, P. (author)
- Trichopoulou, A. (author)
- Benetou, V. (author)
- Tumino, R. (author)
- Panico, S. (author)
- Sieri, S. (author)
- Palli, D. (author)
- Ricceri, F. (author)
- Bueno-de-Mesquita, H. B(as) (author)
- Skeie, G. (author)
- Amiano, P. (author)
- Sanchez, M. J. (author)
- Chirlaque, M. D. (author)
- Barricarte, A. (author)
- Quiros, J. R. (author)
- Buckland, G. (author)
- van Gils, C. H. (author)
- Peeters, P. H. (author)
- Key, T. J. (author)
- Riboli, E. (author)
- Zeleniuch-Jacquotte, A. (author)
- Gunter, M. J. (author)
- Romieu, I. (author)
- Chajes, V. (author)
- show less...
- (creator_code:org_t)
- 2017-01-27
- 2017
- English.
- In: International Journal of Cancer. - : Wiley. - 0020-7136 .- 1097-0215. ; 140:6, s. 1246-1259
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Epidemiological studies have reported inconsistent findings for the association between B vitamins and breast cancer (BC) risk. We investigated the relationship between biomarkers of folate and vitamin B12 and the risk of BC in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Plasma concentrations of folate and vitamin B12 were determined in 2,491 BC cases individually matched to 2,521 controls among women who provided baseline blood samples. Multivariable logistic regression models were used to estimate odds ratios by quartiles of either plasma B vitamin. Subgroup analyses by menopausal status, hormone receptor status of breast tumors (estrogen receptor [ER], progesterone receptor [PR] and human epidermal growth factor receptor 2 [HER2]), alcohol intake and MTHFR polymorphisms (677C > T and 1298A > C) were also performed. Plasma levels of folate and vitamin B12 were not significantly associated with the overall risk of BC or by hormone receptor status. A marginally positive association was found between vitamin B12 status and BC risk in women consuming above the median level of alcohol (ORQ4-Q1=1.26; 95% CI 1.00-1.58; P-trend=0.05). Vitamin B12 status was also positively associated with BC risk in women with plasma folate levels below the median value (ORQ4-Q1=1.29; 95% CI 1.02-162; P-trend=0.03). Overall, folate and vitamin B12 status was not clearly associated with BC risk in this prospective cohort study. However, potential interactions between vitamin B12 and alcohol or folate on the risk of BC deserve further investigation.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- plasma biomarkers
- folate
- vitamin B12
- alcohol
- hormone receptor status
- MTHFR polymorphism
- east cancer
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- International Journal of Cancer (Search for host publication in LIBRIS)
To the university's database
- 8 of 21
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Matejcic, M.
- de Batlle, J.
- Ricci, C.
- Biessy, C.
- Perrier, F.
- Huybrechts, I.
- show more...
- Weiderpass, E.
- Boutron-Ruault, ...
- Cadeau, C.
- His, M.
- Cox, D. G.
- Boeing, H.
- Fortner, R. T.
- Kaaks, R.
- Lagiou, P.
- Trichopoulou, A.
- Benetou, V.
- Tumino, R.
- Panico, S.
- Sieri, S.
- Palli, D.
- Ricceri, F.
- Bueno-de-Mesquit ...
- Skeie, G.
- Amiano, P.
- Sanchez, M. J.
- Chirlaque, M. D.
- Barricarte, A.
- Quiros, J. R.
- Buckland, G.
- van Gils, C. H.
- Peeters, P. H.
- Key, T. J.
- Riboli, E.
- Gylling, Björn
- Zeleniuch-Jacquo ...
- Gunter, M. J.
- Romieu, I.
- Chajes, V.
- show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Cancer and Oncol ...
- Articles in the publication
- International Jo ...
- By the university
- Umeå University
- Karolinska Institutet
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
